Difference between revisions of "YfkJ"

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(Database entries)
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* '''Description:''' general stress protein, [[protein kinases and phosphatases|protein tyrosine phosphatase]] <br/><br/>
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* '''Description:''' general stress protein, [[protein kinases and phosphatases|protein tyrosine phosphatase]], required for protection against paraquat stress  <br/><br/>
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
 
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|style="background:#ABCDEF;" align="center"| '''Product''' || [[protein kinases and phosphatases|protein tyrosine phosphatase]]  
 
|style="background:#ABCDEF;" align="center"| '''Product''' || [[protein kinases and phosphatases|protein tyrosine phosphatase]]  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || survival of ethanol stress
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|style="background:#ABCDEF;" align="center"|'''Function''' || survival of stress conditions
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU07880 yfkJ]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU07880 yfkJ]
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= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
 
{{SubtiWiki category|[[protein modification]]}},
 
{{SubtiWiki category|[[protein modification]]}},
{{SubtiWiki category|[[general stress proteins (controlled by SigB)]]}}
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{{SubtiWiki category|[[general stress proteins (controlled by SigB)]]}},
 +
{{SubtiWiki category|[[resistance against oxidative and electrophile stress]]}}
  
 
= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yfkJ_862004_862474_1 yfkJ] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yfkJ_862004_862474_1 yfkJ] {{PubMed|22383849}}
  
* '''Sigma factor:''' SigA {{PubMed|11532142}}, [[SigB]] {{PubMed|15805528,11532142}}  
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* '''[[Sigma factor]]:''' SigA {{PubMed|11532142}}, [[SigB]] {{PubMed|15805528,11532142}}  
  
 
* '''Regulation:'''  induced by stress ([[SigB]]) {{PubMed|15805528,11532142}}
 
* '''Regulation:'''  induced by stress ([[SigB]]) {{PubMed|15805528,11532142}}
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=References=
 
=References=
  
<pubmed>15866923,15995210,,15805528,11532142  </pubmed>
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<pubmed>15866923,15995210,22582280,15805528,11532142  </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 19:20, 15 September 2013

Gene name yfkJ
Synonyms
Essential no
Product protein tyrosine phosphatase
Function survival of stress conditions
Gene expression levels in SubtiExpress: yfkJ
MW, pI 17 kDa, 4.563
Gene length, protein length 468 bp, 156 aa
Immediate neighbours yfkK, yfkI
Sequences Protein DNA DNA_with_flanks
Genetic context
YfkJ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YfkJ expression.png















Categories containing this gene/protein

protein modification, general stress proteins (controlled by SigB), resistance against oxidative and electrophile stress

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

  • Locus tag: BSU07880

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate (according to Swiss-Prot)
  • Protein family: low molecular weight phosphotyrosine protein phosphatase family (according to Swiss-Prot)
  • Paralogous protein(s): YwlE

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Alexander Reder, Dirk Höper, Ulf Gerth, Michael Hecker
Contributions of individual σB-dependent general stress genes to oxidative stress resistance of Bacillus subtilis.
J Bacteriol: 2012, 194(14);3601-10
[PubMed:22582280] [WorldCat.org] [DOI] (I p)

Lucia Musumeci, Cristina Bongiorni, Lutz Tautz, Robert A Edwards, Andrei Osterman, Marta Perego, Tomas Mustelin, Nunzio Bottini
Low-molecular-weight protein tyrosine phosphatases of Bacillus subtilis.
J Bacteriol: 2005, 187(14);4945-56
[PubMed:15995210] [WorldCat.org] [DOI] (P p)

Ivan Mijakovic, Lucia Musumeci, Lutz Tautz, Dina Petranovic, Robert A Edwards, Peter Ruhdal Jensen, Tomas Mustelin, Josef Deutscher, Nunzio Bottini
In vitro characterization of the Bacillus subtilis protein tyrosine phosphatase YwqE.
J Bacteriol: 2005, 187(10);3384-90
[PubMed:15866923] [WorldCat.org] [DOI] (P p)

Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528] [WorldCat.org] [DOI] (P p)

C W Price, P Fawcett, H Cérémonie, N Su, C K Murphy, P Youngman
Genome-wide analysis of the general stress response in Bacillus subtilis.
Mol Microbiol: 2001, 41(4);757-74
[PubMed:11532142] [WorldCat.org] [DOI] (P p)