Difference between revisions of "YfkJ"

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* '''Description:''' general stress protein, [[protein kinases and phosphatases|protein tyrosine phosphatase]] <br/><br/>
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|style="background:#ABCDEF;" align="center"|'''Function''' || survival of ethanol stress
 
|style="background:#ABCDEF;" align="center"|'''Function''' || survival of ethanol stress
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU07880 yfkJ]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 17 kDa, 4.563   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 17 kDa, 4.563   

Revision as of 15:58, 6 August 2012


Gene name yfkJ
Synonyms
Essential no
Product protein tyrosine phosphatase
Function survival of ethanol stress
Gene expression levels in SubtiExpress: yfkJ
MW, pI 17 kDa, 4.563
Gene length, protein length 468 bp, 156 aa
Immediate neighbours yfkK, yfkI
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YfkJ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YfkJ expression.png
























Categories containing this gene/protein

protein modification, general stress proteins (controlled by SigB)

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

  • Locus tag: BSU07880

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate (according to Swiss-Prot)
  • Protein family: low molecular weight phosphotyrosine protein phosphatase family (according to Swiss-Prot)
  • Paralogous protein(s): YwlE

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Lucia Musumeci, Cristina Bongiorni, Lutz Tautz, Robert A Edwards, Andrei Osterman, Marta Perego, Tomas Mustelin, Nunzio Bottini
Low-molecular-weight protein tyrosine phosphatases of Bacillus subtilis.
J Bacteriol: 2005, 187(14);4945-56
[PubMed:15995210] [WorldCat.org] [DOI] (P p)

Ivan Mijakovic, Lucia Musumeci, Lutz Tautz, Dina Petranovic, Robert A Edwards, Peter Ruhdal Jensen, Tomas Mustelin, Josef Deutscher, Nunzio Bottini
In vitro characterization of the Bacillus subtilis protein tyrosine phosphatase YwqE.
J Bacteriol: 2005, 187(10);3384-90
[PubMed:15866923] [WorldCat.org] [DOI] (P p)

Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528] [WorldCat.org] [DOI] (P p)

C W Price, P Fawcett, H Cérémonie, N Su, C K Murphy, P Youngman
Genome-wide analysis of the general stress response in Bacillus subtilis.
Mol Microbiol: 2001, 41(4);757-74
[PubMed:11532142] [WorldCat.org] [DOI] (P p)