immR

immR
168

transcriptional repressor ([wiki|Xre family]), controls expression of genes of the mobile genetic element ICEBs1, induction by the SOS response or the [protein|A208B4564A50D7BE2630DE40E8FAAF3C16236EE4|rapI]-[protein|F3E14B772A5DA9073ED806A9ADDD9B64F0DFDD5B|phrI] sensory system

locus
BSU_04820
Molecular weight
14.51 kDa
pI
4.99
Protein length
127 aaSequenceBlast
Gene length
384 bpSequenceBlast
function
control of transfer of the mobile genetic element ICEBs1
product
transcriptional repressor ([wiki|Xre family])
essential
no
synonyms
immR, ydcN
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1396 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
531,130 → 531,513
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The protein
Protein family
[wiki|Xre family]
[wiki|Domains]
[wiki|HTH cro/C1-type domain] (aa 7-61) (according to UniProt)
Structure
[PDB|7T8I] [pubmed|35347179]
[AF|P96631]
Effectors of protein activity
binding of [protein|A208B4564A50D7BE2630DE40E8FAAF3C16236EE4|rapI] to ImmR results in loss of DNA-binding activity of ImmR and subsequently in induction of ImmR-repressed genes  [Pubmed|17511812]
Expression and Regulation
Operons
genes
[gene|DD1C8F3A4809785BD6A6047D39B42AB2C605E161|immR]-[gene|1599BBAC05EB62A847F73572CD777BC472301DE8|immA]-[gene|47AE982C5E71F31B5AF04C4F50593C2629F8EDAF|int]
description
[pubmed|22383849]
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[gene|DD1C8F3A4809785BD6A6047D39B42AB2C605E161|immR]→[gene|47AE982C5E71F31B5AF04C4F50593C2629F8EDAF|int]

2024-04-06 12:34:17

Jstuelk

82

ba0e2f39102d664109ce21216f6467994f787a85

0DD14B00F33C60A47598A1CB94B89B6408385882

genes
[gene|DD1C8F3A4809785BD6A6047D39B42AB2C605E161|immR]
description
[pubmed|22383849]
Open in new tab

[gene|DD1C8F3A4809785BD6A6047D39B42AB2C605E161|immR]

2024-04-06 12:34:43

Jstuelk

64

43513217d04389b1ad1d3c7f6b15d70b4fbb5583

B4EA851B8F96FA46D8260EDD5F395A9FEA87518A

Biological materials
Mutant
BKE04820 (Δ[gene|DD1C8F3A4809785BD6A6047D39B42AB2C605E161|immR]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE04820 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTTTATCATCCATTTCA,  downstream forward: _UP4_ATTGACGAATTAAAGAAGAA
BKK04820 (Δ[gene|DD1C8F3A4809785BD6A6047D39B42AB2C605E161|immR]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK04820 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTTTATCATCCATTTCA,  downstream forward: _UP4_ATTGACGAATTAAAGAAGAA
References
Reviews
24995588
Original Publications
17511812,18761623,21036995,35347179

DD1C8F3A4809785BD6A6047D39B42AB2C605E161

Page visits: 3392

Time of last update: 2024-04-16 01:24:41

Author of last update: Jstuelk