Difference between revisions of "YcnK"

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* '''Regulation:'''  
 
* '''Regulation:'''  
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** repressed during logrithmic growth ([[AbrB]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/15101989 PubMed]
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[AbrB]]:  transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/15101989 PubMed]
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  

Revision as of 11:38, 11 June 2009

  • Description: transcription repressor of the ycnJ gene

Gene name ycnK
Synonyms
Essential no
Product transcription repressor
Function regulation of copper uptake
MW, pI 21 kDa, 7.371
Gene length, protein length 570 bp, 190 aa
Immediate neighbours ycnJ, ycnL
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YcnK context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU03960

Phenotypes of a mutant

elevated expression of ycnJ under conditions of copper excess PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: repression of ycnJ expression PubMed
  • Protein family: DeoR family of transcription factors
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s): copper acts as corepressor PubMed
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Mohamed Marahiel, Marburg University, Germany homepage

Your additional remarks

References

Shashi Chillappagari, Marcus Miethke, Hein Trip, Oscar P Kuipers, Mohamed A Marahiel
Copper acquisition is mediated by YcnJ and regulated by YcnK and CsoR in Bacillus subtilis.
J Bacteriol: 2009, 191(7);2362-70
[PubMed:19168619] [WorldCat.org] [DOI] (I p)

  1. Chillappagari S, Miethke M, Trip H, Kuipers OP, Marahiel MA (2009) Copper acquisition is mediated by YcnJ and regulated by YcnK and CsoR in Bacillus subtilis. J. Bacteriol. 191: 2362-2370. PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed