YcnJ

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  • Description: copper transporter

Gene name ycnJ
Synonyms
Essential no
Product copper transporter
Function uptake of copper
Gene expression levels in SubtiExpress: ycnJ
MW, pI 59 kDa, 10.098
Gene length, protein length 1623 bp, 541 aa
Immediate neighbours ycnI, ycnK
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YcnJ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YcnJ expression.png
























Categories containing this gene/protein

transporters/ other, trace metal homeostasis (Cu, Zn, Ni, Mn, Mo), membrane proteins

This gene is a member of the following regulons

CsoR regulon, YcnK regulon

The gene

Basic information

  • Locus tag: BSU03950

Phenotypes of a mutant

growth-defective under copper-limiting conditions PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: uptake of copper PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
    • eightfold induction under copper-limiting conditions (YcnK, CsoR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Mohamed Marahiel, Marburg University, Germany homepage

Your additional remarks

References

Shashi Chillappagari, Marcus Miethke, Hein Trip, Oscar P Kuipers, Mohamed A Marahiel
Copper acquisition is mediated by YcnJ and regulated by YcnK and CsoR in Bacillus subtilis.
J Bacteriol: 2009, 191(7);2362-70
[PubMed:19168619] [WorldCat.org] [DOI] (I p)