Difference between revisions of "YclJ"

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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU03750 yclJ]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU03750 yclJ]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/YclJ YclJ]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=YclJ YclJ]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 26 kDa, 4.58   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 26 kDa, 4.58   

Revision as of 15:11, 11 November 2013

  • Description: two-component response regulator, active under anaerobic conditions

Gene name yclJ
Synonyms
Essential no
Product two-component response regulator
Function unknown
Gene expression levels in SubtiExpress: yclJ
Interactions involving this protein in SubtInteract: YclJ
MW, pI 26 kDa, 4.58
Gene length, protein length 681 bp, 227 aa
Immediate neighbours yclI, yclK
Sequences Protein DNA DNA_with_flanks
Genetic context
YclJ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YclJ expression.png
























Categories containing this gene/protein

transcription factors and their control, phosphoproteins

This gene is a member of the following regulons

ResD regulon

The YclJ regulon

The gene

Basic information

  • Locus tag: BSU03750

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: OmpR family of two-component response regulators
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylated by YclK on an Asp residue
  • Cofactor(s):
  • Effectors of protein activity: phosphorylation likely affects DNA-binding activity

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
    • expressed under anaerobic conditions (ResD) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Mitsuo Ogura, Kensuke Tsukahara, Teruo Tanaka
Identification of the sequences recognized by the Bacillus subtilis response regulator YclJ.
Arch Microbiol: 2010, 192(7);569-80
[PubMed:20512483] [WorldCat.org] [DOI] (I p)

Elisabeth Härtig, Hao Geng, Anja Hartmann, Angela Hubacek, Richard Münch, Rick W Ye, Dieter Jahn, Michiko M Nakano
Bacillus subtilis ResD induces expression of the potential regulatory genes yclJK upon oxygen limitation.
J Bacteriol: 2004, 186(19);6477-84
[PubMed:15375128] [WorldCat.org] [DOI] (P p)

C Fabret, V A Feher, J A Hoch
Two-component signal transduction in Bacillus subtilis: how one organism sees its world.
J Bacteriol: 1999, 181(7);1975-83
[PubMed:10094672] [WorldCat.org] [DOI] (P p)