Difference between revisions of "YcdA"

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* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
** [[Abh]]and [[AbrB]]: synergistic transcription repression{{PubMed|20817675}}
+
** [[Abh]] and [[AbrB]]: synergistic transcription repression {{PubMed|20817675}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''

Revision as of 06:24, 18 September 2010

  • Description: unknown

Gene name ycdA
Synonyms
Essential no
Product unknown
Function unknown
MW, pI 39 kDa, 4.706
Gene length, protein length 1062 bp, 354 aa
Immediate neighbours yccK, ycdB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YcdA context.gif
This image was kindly provided by SubtiList




The gene

Basic information

  • Locus tag: BSU02780

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot), membrane associated PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: ycdA (according to DBTBS)
  • Regulation:
  • Regulatory mechanism:
  • Additional information:
    • The mRNA has a long 5' leader region. This may indicate RNA-based regulation PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Onuma Chumsakul, Hiroki Takahashi, Taku Oshima, Takahiro Hishimoto, Shigehiko Kanaya, Naotake Ogasawara, Shu Ishikawa
Genome-wide binding profiles of the Bacillus subtilis transition state regulator AbrB and its homolog Abh reveals their interactive role in transcriptional regulation.
Nucleic Acids Res: 2011, 39(2);414-28
[PubMed:20817675] [WorldCat.org] [DOI] (I p)

Irnov Irnov, Cynthia M Sharma, Jörg Vogel, Wade C Winkler
Identification of regulatory RNAs in Bacillus subtilis.
Nucleic Acids Res: 2010, 38(19);6637-51
[PubMed:20525796] [WorldCat.org] [DOI] (I p)

Hannes Hahne, Susanne Wolff, Michael Hecker, Dörte Becher
From complementarity to comprehensiveness--targeting the membrane proteome of growing Bacillus subtilis by divergent approaches.
Proteomics: 2008, 8(19);4123-36
[PubMed:18763711] [WorldCat.org] [DOI] (I p)