YcbJ

• Description: similar to macrolide 2'-phosphotransferase
  
  

Gene name	ycbJ
Synonyms
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: ycbJ
MW, pI	34 kDa, 4.565
Gene length, protein length	918 bp, 306 aa
Immediate neighbours	ycbH, rtpA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

resistance against toxins/ antibiotics

This gene is a member of the following regulons

AbrB regulon, YcbG regulon

The gene

Basic information

• Locus tag: BSU02520

Database entries

• BsubCyc: BSU02520

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: aminoglycoside phosphotransferase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU02520

• Structure:

• UniProt: P42242

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: ycbC-ycbD-ycbE-ycbF-ycbG-ycbH-ycbJ PubMed

• Expression browser: ycbJ PubMed

• Sigma factor:

• Regulation:
  • induced by D-glucarate/galactarate (YcbG) PubMed
  • repressed during logarithmic phase (AbrB) PubMed

• Regulatory mechanism:
  • YcbG: transcription repression PubMed
  • AbrB: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Allison V Banse, Arnaud Chastanet, Lilah Rahn-Lee, Errett C Hobbs, Richard Losick
Parallel pathways of repression and antirepression governing the transition to stationary phase in Bacillus subtilis.
Proc Natl Acad Sci U S A: 2008, 105(40);15547-52
[PubMed:18840696] [WorldCat.org] [DOI] (I p)

Shigeo Hosoya, Kunio Yamane, Michio Takeuchi, Tsutomu Sato
Identification and characterization of the Bacillus subtilis D-glucarate/galactarate utilization operon ycbCDEFGHJ.
FEMS Microbiol Lett: 2002, 210(2);193-9
[PubMed:12044674] [WorldCat.org] [DOI] (P p)