Difference between revisions of "YcbH"

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|style="background:#ABCDEF;" align="center"|'''Function''' || galactarate utilization
 
|style="background:#ABCDEF;" align="center"|'''Function''' || galactarate utilization
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU02510 ycbH]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU02510 ycbH]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 54 kDa, 5.705   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 54 kDa, 5.705   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ycbG]]'', ''[[ycbJ]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ycbG]]'', ''[[ycbJ]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12045&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU02510 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU02510 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU02510 Advanced_DNA]
 
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Revision as of 12:03, 13 May 2013

  • Description: galactarate dehydratase

Gene name ycbH
Synonyms garD
Essential no
Product galactarate dehydratase
Function galactarate utilization
Gene expression levels in SubtiExpress: ycbH
MW, pI 54 kDa, 5.705
Gene length, protein length 1530 bp, 510 aa
Immediate neighbours ycbG, ycbJ
Sequences Protein DNA Advanced_DNA
Genetic context
YcbH context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YcbH expression.png
























Categories containing this gene/protein

utilization of specific carbon sources

This gene is a member of the following regulons

YcbG regulon

The gene

Basic information

  • Locus tag: BSU02510

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: d-galactarate = 5-dehydro-4-deoxy-D-glucarate + H2O (according to Swiss-Prot)
  • Protein family: uxaA family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation: induced by D-glucarate/galactarate (YcbG) PubMed
  • Regulatory mechanism: YcbG: transcription repression PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Shigeo Hosoya, Kunio Yamane, Michio Takeuchi, Tsutomu Sato
Identification and characterization of the Bacillus subtilis D-glucarate/galactarate utilization operon ycbCDEFGHJ.
FEMS Microbiol Lett: 2002, 210(2);193-9
[PubMed:12044674] [WorldCat.org] [DOI] (P p)