petA

168

phosphatidylethanolamine transporter, distribution of phosphatidylethanolamine between inner and outer leaflets of the membrane

locus: BSU_02280

Molecular weight: 18.20 kDa

pI: 9.48

Protein length: 162 aa

Gene length: 489 bp

function: export of phosphatidylethanolamine

product: phosphatidylethanolamine transporter

essential: no

synonyms: ybfM

List of homologs in different organisms, belongs to COG0586 (Galperin et al., 2021)

Gene

Coordinates: 248,268 → 248,756

Phenotypes of a mutant

• increased resistance to duramycin [pubmed|37155911]

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The protein

Catalyzed reaction/ biological activity

• export of phosphatidylethanolamine to the outer side of the cell membrane [pubmed|37155911]

Protein family

• dedA family (with [protein|289828D37CF5422908316ED2EF1AEAE76F84161D|uptA] and [protein|96CE303E9F757FBEBDEA5ADC8481697E2CD1361A|ykoX], according to UniProt) [pubmed|23086209]

Structure

• [AF|O31453]

Paralogous protein(s)

• [protein|289828D37CF5422908316ED2EF1AEAE76F84161D|uptA]
• [protein|96CE303E9F757FBEBDEA5ADC8481697E2CD1361A|ykoX], (30%)

[wiki|Localization]

• cell membrane (according to UniProt)

Biological materials

Mutant

• BKE02280 (Δ[gene|B2C089DCE51CA0CB11947FCD6F4EFAFF66269829|petA]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE02280 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_GTAATCCGCTATGAGCTGCT,  downstream forward: _UP4_ATCGGAAGGGTTATAGGGAT
• BKK02280 (Δ[gene|B2C089DCE51CA0CB11947FCD6F4EFAFF66269829|petA]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK02280 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_GTAATCCGCTATGAGCTGCT,  downstream forward: _UP4_ATCGGAAGGGTTATAGGGAT

Reviews

• 23086209

References

• 14762009,37155911