YabJ

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  • Description: required for activity of PurR

Gene name yabJ
Synonyms
Essential no
Product unknown
Function regulation of purine biosynthesis
MW, pI 13 kDa, 5.134
Gene length, protein length 375 bp, 125 aa
Immediate neighbours purR, spoVG
Gene sequence (+200bp) Protein sequence
Genetic context
YabJ context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: YjgF family
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions: forms a trimer PubMed
  • Localization:

Database entries

  • Swiss prot entry:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation: negative autoregulation PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Weng et al. (1995) Identification of the Bacillus subtilis pur operon repressor. Proc. Natl. Acad. Sci. USA 92: 7455-7459. PubMed
  2. Sinha et al. (1999) Crystal structure of Bacillus subtilis YabJ, a purine regulatory protein and member of the highly conserved YjgF family.Proc. Natl. Acad. Sci. USA 96: 13074-13079. PubMed
  3. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed