XylR

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  • Description: transcription repressor of the xylAB and xynPB operons

Gene name xylR
Synonyms
Essential no
Product transcriptional repressor
Function control of xylose and xylan utilization
MW, pI 38 kDa, 5.819
Gene length, protein length 1050 bp, 350 aa
Immediate neighbours
Gene sequence (+200bp) Protein sequence
Genetic context
XylR context.gif



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: transcription repression of the xylA-xylB and the xynP-xynB operons
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: inducer: xylose
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry:
  • E.C. number:

Additional information

Expression and regulation

  • Operon: xylR
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Wolfgang Hillen, Erlangen University, Germany Homepage

Your additional remarks

References

  1. Dahl, M. K., Schmiedel, D., and Hillen, W. (1995) Glucose and glucose-6-phosphate interaction with Xyl repressor proteins from Bacillus spp. may contribute to regulation of xylose utilization. J Bacteriol 177: 5467-5472. PubMed
  2. Kauder C, Allmansberger R, Gärtner D, Schmiedel D, Hillen W. 1993. An operator binding-negative mutation of Xyl repressor from Bacillus subtilis is trans dominant in Bacillus megaterium. FEMS Microbiol. Lett. 109:81-84. PubMed
  3. Kreuzer P, Gärtner D, Allmansberger R, Hillen W. 1989. Identification and sequence analysis of the Bacillus subtilis W23 xylR gene and xyl operator. J. Bacteriol. 171:3840-3845. PubMed
  4. Gärtner D, Degenkolb J, Ripperger JAE, Allmansberger R, Hillen W. 1992. Regulation of the Bacillus subtilis W23 xylose utilization operon: interaction of Xyl repressor with xyl operator and the inducer xylose. Mol. Gen. Genet. 232:415-422 PubMed
  5. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed