Difference between revisions of "Xpt"
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=== Database entries === | === Database entries === | ||
| − | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1Y0B 1Y0B], [http://www.rcsb.org/pdb/explore.do?structureId=2FXV 2FXV] (complex with GMP) | + | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1Y0B 1Y0B], [http://www.rcsb.org/pdb/explore.do?structureId=2FXV 2FXV] (complex with GMP), [http://www.rcsb.org/pdb/explore.do?structureId=1Y27 1Y27] (the riboswitch in complex with guanine) |
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P42085 P42085] | * '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P42085 P42085] | ||
Revision as of 20:19, 5 June 2009
- Description: xanthine phosphoribosyltransferase
| Gene name | xpt |
| Synonyms | |
| Essential | no |
| Product | xanthine phosphoribosyltransferase |
| Function | purine salvage and interconversion |
| MW, pI | 20 kDa, 5.835 |
| Gene length, protein length | 582 bp, 194 aa |
| Immediate neighbours | pbuX, ypwA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU22070
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: XMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine (according to Swiss-Prot)
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Swiss prot entry: P42085
- KEGG entry: [3]
- E.C. number: 2.4.2.22
Additional information
- subject to Clp-dependent proteolysis upon glucose starvation PubMed
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information: subject to Clp-dependent proteolysis upon glucose starvation PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
