XlyB

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  • Description: N-acetylmuramoyl-L-alanine amidase

Gene name xlyB
Synonyms yjpB
Essential no
Product N-acetylmuramoyl-L-alanine amidase
Function PBSX prophage-mediated lysis
Gene expression levels in SubtiExpress: xlyB
MW, pI 33 kDa, 9.802
Gene length, protein length 951 bp, 317 aa
Immediate neighbours yjpA, yjqA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
XlyB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
XlyB expression.png
























Categories containing this gene/protein

cell wall degradation/ turnover, phage-related functions

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU12460

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides (according to Swiss-Prot)
  • Protein family: LysM repeat (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information: the mRNA is very stable (half-life > 15 min) PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

G Hambraeus, C von Wachenfeldt, L Hederstedt
Genome-wide survey of mRNA half-lives in Bacillus subtilis identifies extremely stable mRNAs.
Mol Genet Genomics: 2003, 269(5);706-14
[PubMed:12884008] [WorldCat.org] [DOI] (P p)