Difference between revisions of "XlyB"
| Line 66: | Line 66: | ||
* '''Catalyzed reaction/ biological activity:''' Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides (according to Swiss-Prot) | * '''Catalyzed reaction/ biological activity:''' Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides (according to Swiss-Prot) | ||
| − | * '''Protein family:''' | + | * '''Protein family:''' |
* '''Paralogous protein(s):''' | * '''Paralogous protein(s):''' | ||
| Line 75: | Line 75: | ||
* '''[[Domains]]:''' | * '''[[Domains]]:''' | ||
| − | ** contains | + | ** contains a N-acetylglucosamine-polymer-binding [[LysM domain]] {{PubMed|18430080}} |
** contains an amidase_2 domain (like [[BlyA]], [[CwlA]], [[CwlH]], [[XlyB]]) | ** contains an amidase_2 domain (like [[BlyA]], [[CwlA]], [[CwlH]], [[XlyB]]) | ||
Revision as of 14:54, 27 December 2013
- Description: N-acetylmuramoyl-L-alanine amidase
| Gene name | xlyB |
| Synonyms | yjpB |
| Essential | no |
| Product | N-acetylmuramoyl-L-alanine amidase |
| Function | PBSX prophage-mediated lysis |
| Gene expression levels in SubtiExpress: xlyB | |
| MW, pI | 33 kDa, 9.802 |
| Gene length, protein length | 951 bp, 317 aa |
| Immediate neighbours | yjpA, yjqA |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
cell wall degradation/ turnover, phage-related functions, PBSX prophage
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU12460
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides (according to Swiss-Prot)
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
- Localization:
- secreted (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: O34391
- KEGG entry: [2]
- E.C. number: 3.5.1.28
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information: the mRNA is very stable (half-life > 15 min) PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Girbe Buist, Anton Steen, Jan Kok, Oscar P Kuipers
LysM, a widely distributed protein motif for binding to (peptido)glycans.
Mol Microbiol: 2008, 68(4);838-47
[PubMed:18430080]
[WorldCat.org]
[DOI]
(I p)
Original publications
G Hambraeus, C von Wachenfeldt, L Hederstedt
Genome-wide survey of mRNA half-lives in Bacillus subtilis identifies extremely stable mRNAs.
Mol Genet Genomics: 2003, 269(5);706-14
[PubMed:12884008]
[WorldCat.org]
[DOI]
(P p)
