Xis

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  • Description: excisionase

Gene name xis
Synonyms ydzC, sacV
Essential no
Product excisionase
Function excision of the conjugative transposon ICEBs1 from the trnS-leu2 locus
MW, pI 7 kDa, 9.64
Gene length, protein length 192 bp, 64 aa
Immediate neighbours immR, ydcO
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SacV context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

mobile genetic elements

This gene is a member of the following regulons

ImmR regulon

The gene

Basic information

  • Locus tag: BSU04830

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: excision of conjugative transposon PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Was reported to be involved in the regulation of the levansucrase gene (sacB)

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Catherine A Lee, Jennifer M Auchtung, Rita E Monson, Alan D Grossman
Identification and characterization of int (integrase), xis (excisionase) and chromosomal attachment sites of the integrative and conjugative element ICEBs1 of Bacillus subtilis.
Mol Microbiol: 2007, 66(6);1356-69
[PubMed:18005101] [WorldCat.org] [DOI] (P p)

Jennifer M Auchtung, Catherine A Lee, Katherine L Garrison, Alan D Grossman
Identification and characterization of the immunity repressor (ImmR) that controls the mobile genetic element ICEBs1 of Bacillus subtilis.
Mol Microbiol: 2007, 64(6);1515-28
[PubMed:17511812] [WorldCat.org] [DOI] (P p)