Wish List

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Revision as of 15:56, 4 December 2008 by 134.76.70.252 (talk)
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SubtiWiki is all about making a useful tool for the Bacillus community. It is thus very important to receive feedback on what the community needs.

We believe that there are many types of users, with different requirements. For example:

  • You could be a molecular biologist wanting to know the sequence of your gene of interest to make a PCR
  • You find a reference to a gene in a paper you are reading and are interested to know more about that gene
  • You have some hypotheses in mind and want to collect some facts to get inspired
  • You have a piece of information that you need almost daily and want to make it available not only to you, but also your group or to the whole community

In all of these cases, you will need different kind of information and you would favor one presentation over another.

Essential facts (what every gene page should have)

  • Gene name
  • Function
  • Synonyms
  • Summary (for not self-explanatory functions)
  • DNA and protein sequence
  • Essential?
  • Genetic context
  • References

Facts that would be nice to have

About the gene

  • Coordinates

About the protein

  • catalyzed reaction (for enzymes)
    • Kinetics
  • protein family
  • structure (or should it just be linked to the database?)
  • domains
  • Modifications
  • Effectors of protein activity
  • Interactions
  • Localization
  • MW
  • pI

About the expression of the protein

  • Operon
  • Sigma Factor
  • Regulation
    • Inducers
    • Repressors
  • Regulatory mechanism

About available biological materials

  • Mutants
  • Expression vectors
  • lacZ fusions
  • GFP fusions
  • Antibodies

== About the conservation of the gene

Other stuff

  • Groups working on the Gene

Databases that should be linked to the page

  • PDB (Protein Data Bank) - Structures
  • Uniprot
  • KEGG
  • SubtiList (?)