Difference between revisions of "ValS"

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(Expression and regulation)
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* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** induced by valine limitation ([[T-box]]) {{PubMed|19258532}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[T-box]]: [[RNA switch]], transcriptional antitermination {{PubMed|19258532}}
  
* '''Additional information:'''  
+
* '''Additional information:'''
  
 
=Biological materials =
 
=Biological materials =

Revision as of 20:11, 1 October 2009

  • Description: valyl-tRNA synthetase

Gene name valS
Synonyms
Essential yes PubMed
Product valyl-tRNA synthetase
Function translation
Metabolic function and regulation of this protein in SubtiPathways:
tRNA charging, Folate
MW, pI 101 kDa, 4.868
Gene length, protein length 2640 bp, 880 aa
Immediate neighbours folC, ysxE
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
ValS context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU28090

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val) (according to Swiss-Prot)
  • Protein family: ValS type 1 subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References