Difference between revisions of "UxuA"

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** ''[[yjmC]]-[[yjmD]]-[[uxuA]]-[[yjmF]]-[[exuT]]-[[exuR]]-[[uxaB]]-[[uxaA]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/9882655 PubMed]
 
** ''[[yjmC]]-[[yjmD]]-[[uxuA]]-[[yjmF]]-[[exuT]]-[[exuR]]-[[uxaB]]-[[uxaA]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/9882655 PubMed]
  
* '''[[Sigma factor]]:'''  
+
* '''[[Sigma factor]]:''' [[SigE]] {{PubMed|15699190}}
 
** ''[[uxaC]]'': [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/9882655 PubMed]
 
** ''[[uxaC]]'': [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/9882655 PubMed]
 
** ''[[yjmC]]'': [[SigE]] [http://www.ncbi.nlm.nih.gov/sites/entrez/9882655 PubMed]
 
** ''[[yjmC]]'': [[SigE]] [http://www.ncbi.nlm.nih.gov/sites/entrez/9882655 PubMed]

Revision as of 14:36, 31 July 2009

  • Description: D-mannonate hydrolyase

Gene name uxuA
Synonyms yjmE
Essential no
Product D-mannonate hydrolyase
Function hexuronate utilization
MW, pI 40 kDa, 4.92
Gene length, protein length 1077 bp, 359 aa
Immediate neighbours yjmD, yjmF
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
UxuA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU12340

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O (according to Swiss-Prot)
  • Protein family: mannonate dehydratase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Y Miwa, A Nakata, A Ogiwara, M Yamamoto, Y Fujita
Evaluation and characterization of catabolite-responsive elements (cre) of Bacillus subtilis.
Nucleic Acids Res: 2000, 28(5);1206-10
[PubMed:10666464] [WorldCat.org] [DOI] (I p)

K R Mekjian, E M Bryan, B W Beall, C P Moran
Regulation of hexuronate utilization in Bacillus subtilis.
J Bacteriol: 1999, 181(2);426-33
[PubMed:9882655] [WorldCat.org] [DOI] (P p)

Carlo Rivolta, Blazenka Soldo, Vladimir Lazarevic, Bernard Joris, Catherine Mauël, Dimitri Karamat
A 35.7 kb DNA fragment from the Bacillus subtilis chromosome containing a putative 12.3 kb operon involved in hexuronate catabolism and a perfectly symmetrical hypothetical catabolite-responsive element.
Microbiology (Reading): 1998, 144 ( Pt 4);877-884
[PubMed:9579062] [WorldCat.org] [DOI] (P p)