Difference between revisions of "UxaC"

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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:'''  
+
* '''Operon:''' uxaC-yjmB-yjmC
  
* '''[[Sigma factor]]:'''  
+
* '''[[Sigma factor]]:''' [[SigA]]
  
 
* '''Regulation:''' repressed by glucose ([[CcpA]])   
 
* '''Regulation:''' repressed by glucose ([[CcpA]])   

Revision as of 12:50, 30 May 2009

  • Description: glucuronate isomerase (D-glucuronate, D-galacturonate)

Gene name uxaC
Synonyms yjmA
Essential no
Product glucuronate isomerase (D-glucuronate, D-galacturonate)
Function hexuronate utilization
MW, pI 54 kDa, 5.174
Gene length, protein length 1419 bp, 473 aa
Immediate neighbours ndh, yjmB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
UxaC context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: D-glucuronate = D-fructuronate (according to Swiss-Prot)
  • Protein family: uronate isomerase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:

Additional information

Expression and regulation

  • Operon: uxaC-yjmB-yjmC
  • Regulation: repressed by glucose (CcpA)
  • Regulatory mechanism: CcpA: transcription repression
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed