uxaC
168
glucuronate isomerase (D-glucuronate, D-galacturonate)
locus
BSU_12300
Molecular weight
54.44 kDa
pI
5.17
function
hexuronate utilization
product
glucuronate isomerase (D-glucuronate, D-galacturonate)
essential
no
ec
5.3.1.12
synonyms
uxaC, yjmA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1904 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,300,450 1,301,871
The protein
Catalyzed reaction/ biological activity
D-glucuronate --> D-fructuronate (according to UniProt)
aldehydo-D-galacturonate --> keto-D-tagaturonate (according to UniProt)
Protein family
[wiki|metallo-dependent hydrolases superfamily] (according to UniProt)
Structure
[PDB|3IAC] (from Salmonella typhimurium, 49% identity)
[AF|O34808]
Biological materials
Mutant
MGNA-A365 (yjmA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/365 NBRP B. subtilis, Japan]
BKE12300 ([gene|5A0C29C7E218701727523885D01A48D02266B421|uxaC]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE12300 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTCCTCACCGTCTTTCA, downstream forward: _UP4_TAACAAAGTGTCCGCTCAGT
BKK12300 ([gene|5A0C29C7E218701727523885D01A48D02266B421|uxaC]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK12300 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTCCTCACCGTCTTTCA, downstream forward: _UP4_TAACAAAGTGTCCGCTCAGT
References
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Time of last update: 2024-04-24 06:02:53
Author of last update: Melvin.boenninger