Difference between revisions of "UvrC"

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(The protein)
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:'''  
+
* '''Operon:''' ''uvrC'' {{PubMed|16267290}}
  
 
* '''[[Sigma factor]]:'''  
 
* '''[[Sigma factor]]:'''  
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
** repressed when no DNA damage is present ([[LexA]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/16267290 PubMed]
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** induced upon DNA damage ([[LexA]]) {{PubMed|16267290}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
** [[LexA]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/16267290 PubMed]
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** [[LexA]]: transcription repression {{PubMed|16267290}}]
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  

Revision as of 20:51, 14 December 2009

  • Description: excinuclease ABC (subunit C)

Gene name uvrC
Synonyms uvrB
Essential no
Product excinuclease ABC (subunit C)
Function DNA repair after UV damage
MW, pI 69 kDa, 9.503
Gene length, protein length 1794 bp, 598 aa
Immediate neighbours ask, trxA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
UvrC context.gif
This image was kindly provided by SubtiList





The gene

Basic information

  • Locus tag: BSU28490

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: uvrC family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure: 3C65 (5' endonuclease domain, Geobacillus stearothermophilus)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original Publications