Universally conserved proteins

These proteins are present in all genomes sequenced so far, from archaea and bacteria to man. So, one can say, that there is no life on earth without this small set of proteins

Glycolytic enzymes

• Eno enolase
• Pgk phosphoglycerate kinase

Ribosomal proteins

RplA, RplB, RplC, RplE, RplF, RplK, RplN, RplR, RplV, RpsB, RpsC, RpsD, RpsE, RpsG, RpsH, RpsJ, RpsM, RpsQ, RpsS

Cellular processes

• GroES chaperonine
• SecY secretion

Nucleotide metabolism

• Prs phosphoribosyl-PP-synthetase
• Apt adenine phosphoribosyltransferase
• TruA pseudouridylate synthase

Aminoacyl tRNA synthetases

ArgS, PheS, GltX

Degradation of glycoproteins

• Gcp sialo-glycoprotein endopeptidase