Difference between revisions of "Ung"

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|style="background:#ABCDEF;" align="center"|'''Function''' || DNA repair  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || DNA repair  
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU37970 ung]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU37970 ung]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/Ung Ung]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/Ung Ung]
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ywdH]]'', ''[[ywdF]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ywdH]]'', ''[[ywdF]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15823&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU37970 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU37970 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU37970 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:ung_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ung_context.gif]]

Revision as of 14:09, 13 May 2013

  • Description: uracil-DNA glycosylase

Gene name ung
Synonyms ipa-57d, ywdG
Essential no
Product uracil-DNA glycosylase
Function DNA repair
Gene expression levels in SubtiExpress: ung
Interactions involving this protein in SubtInteract: Ung
MW, pI 25 kDa, 8.782
Gene length, protein length 675 bp, 225 aa
Immediate neighbours ywdH, ywdF
Sequences Protein DNA Advanced_DNA
Genetic context
Ung context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Ung expression.png
























Categories containing this gene/protein

DNA repair/ recombination

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU37970

Phenotypes of a mutant

  • increased mutation rates PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: removes uracil preferentially from single-stranded DNA over double-stranded DNA, exhibiting higher preference for U:G than U:A mismatches PubMed
  • Protein family: uracil-DNA glycosylase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 3A7N (from Mycobacterium tuberculosis, 42% identity) PubMed
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
    • expressed throughout growth and staionary phase PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed