udk

168

uridine kinase

locus: BSU_27330

Molecular weight: 24.34 kDa

pI: 5.38

Protein length: 211 aa

Gene length: 636 bp

function: UMP synthesis

product: uridine kinase

essential: no

ec: 2.7.1.48

synonyms: udk

List of homologs in different organisms, belongs to COG0572 (Galperin et al., 2021)

Gene

Coordinates: 2,792,218  2,792,853

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The protein

Catalyzed reaction/ biological activity

• ATP + uridine --> ADP + H⁺ + UMP (according to UniProt)
• ATP + cytidine --> ADP + CMP + H⁺ (according to UniProt)

Protein family

• uridine kinase family (single member, according to UniProt)

Structure

• [PDB|3W8R] (from Thermus thermophilus, 55% identity)
• [AF|O32033]

Biological materials

Mutant

• BKE27330 ([gene|A659D9894E777D8A99707CB750DF2918AEE06CE9|udk]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE27330 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_TACTGGATTCTTACCCATGG,  downstream forward: _UP4_TAATACCATAGCATAGACAT
• BKK27330 ([gene|A659D9894E777D8A99707CB750DF2918AEE06CE9|udk]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK27330 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_TACTGGATTCTTACCCATGG,  downstream forward: _UP4_TAATACCATAGCATAGACAT