Difference between revisions of "TsaE"

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(The protein)
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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:'''  the corresponding ''E. coli'' protein is involved in the control of the activity of the [[Gcp]] homolog
+
* '''Catalyzed reaction/ biological activity:'''  the corresponding ''E. coli'' protein is involved in the control of the activity of the [[Gcp]] homolog [http://www.ncbi.nlm.nih.gov/sites/entrez/19376873 PubMed]
  
 
* '''Protein family:'''
 
* '''Protein family:'''
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:''' dimerizes and oligomerizes  [http://www.ncbi.nlm.nih.gov/sites/entrez/19246765 PubMed], the corresponding ''E. coli'' protein interacts with the protein corresponding to [[YdiC]]
+
* '''Interactions:''' dimerizes and oligomerizes  [http://www.ncbi.nlm.nih.gov/sites/entrez/19246765 PubMed], the corresponding ''E. coli'' protein interacts with the protein corresponding to [[YdiC]] [http://www.ncbi.nlm.nih.gov/sites/entrez/19376873 PubMed]
  
 
* '''Localization:''' cytoplasm with the excepton of the nucleoid region  [http://www.ncbi.nlm.nih.gov/sites/entrez/19246765 PubMed]
 
* '''Localization:''' cytoplasm with the excepton of the nucleoid region  [http://www.ncbi.nlm.nih.gov/sites/entrez/19246765 PubMed]

Revision as of 09:36, 25 April 2009

  • Description: P-loop ATPase

Gene name ydiB
Synonyms
Essential no
Product P-loop ATPase
Function unknown
MW, pI 17 kDa, 4.597
Gene length, protein length 474 bp, 158 aa
Immediate neighbours thiL, ydiC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YdiB context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

reduced growth rate PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: the corresponding E. coli protein is involved in the control of the activity of the Gcp homolog PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information: K(M) for ATP: 60 myM, V(max) 10 nmol/min PubMed
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions: dimerizes and oligomerizes PubMed, the corresponding E. coli protein interacts with the protein corresponding to YdiC PubMed
  • Localization: cytoplasm with the excepton of the nucleoid region PubMed

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry: [2]
  • E.C. number:

Additional information

ATPase activity is required for in vivo function of the protein PubMed

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Hunt, A., Rawlins, J. P., Thomaides, H. B., and Errington, J. (2006) Functional analysis of 11 putative essential genes in Bacillus subtilis. Microbiology 152, 2895-2907. PubMed
  2. Karst JC, Foucher AE, Campbell TL, Di Guilmi AM, Stroebel D, Mangat CS, Brown ED, Jault JM (2009) The ATPase activity of an 'essential' Bacillus subtilis enzyme, YdiB, is required for its cellular function and is modulated by oligomerization. Microbiology 155: 944-965. PubMed
  3. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed