trpP

168

S protein of tryptophan [wiki|ECF transporter]

locus: BSU_10010

Molecular weight: 18.13 kDa

pI: 11.15

Protein length: 172 aa

Gene length: 519 bp

function: tryptophan uptake

product: S protein of tryptophan [wiki|ECF transporter]

essential: no

synonyms: trpP, yhaG

List of homologs in different organisms

Gene

Coordinates: 1,074,646  1,075,164

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The protein

Protein family

• vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family (with [protein|9685A380F95F1A73A693B53E4D35A1CB51043FEC|thiT] and [protein|7DD4BB8222B2EFE81C32C5521A29256095B9D6C1|ypdP], according to UniProt)

Structure

• [AF|O07515]

[wiki|Localization]

• cell membrane (according to UniProt)

Expression and Regulation

Other regulations

• [protein|E030E80134E9DED6ADBC73C7C7435024CDFD38B9|mtrB]: translation inhibition, at an [wiki|RNA switch], the [protein|E030E80134E9DED6ADBC73C7C7435024CDFD38B9|mtrB] binding site overlaps the Shine-DAlgarno sequence and translation initation region, [protein|E030E80134E9DED6ADBC73C7C7435024CDFD38B9|mtrB] binds in the presence of tryptophan [Pubmed|10735881]

Biological materials

Mutant

• MGNA-A686 (yhaG::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/686 NBRP B. subtilis, Japan]
• BKE10010 ([gene|97573C2D4FD8BE6B4C749C0644D053C9A0CBFFF3|trpP]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE10010 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATAACTATGCTCTCCTCTG,  downstream forward: _UP4_TAATTGTCACACAAAACCTC
• BKK10010 ([gene|97573C2D4FD8BE6B4C749C0644D053C9A0CBFFF3|trpP]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK10010 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATAACTATGCTCTCCTCTG,  downstream forward: _UP4_TAATTGTCACACAAAACCTC

References

Reviews

• 20497229,22574898,24362466

Original Publications

• 10735881,14702295