Difference between revisions of "TrpC"

From SubtiWiki
Jump to: navigation, search
(References)
Line 90: Line 90:
 
=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:''' ''[[trpE]]-[[trpD]]-[[trpC]]-[[trpF]]-[[trpB]]-[[trpA]]''
+
* '''Operon:''' ''[[trpE]]-[[trpD]]-[[trpC]]-[[trpF]]-[[trpB]]-[[trpA]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/3924737 PubMed]
  
* '''[[Sigma factor]]:''' [[SigA]]
+
* '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/6436812 PubMed]
  
* '''Regulation:''' induction by tryptophan ([[MtrB| TRAP]])
+
* '''Regulation:''' induction by tryptophan ([[MtrB| TRAP]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/1551827 PubMed]
  
* '''Regulatory mechanism:''' [[MtrB| TRAP]]: binding to the mRNA in the presence of tryptophan, this results in transcription termination
+
* '''Regulatory mechanism:''' [[MtrB| TRAP]]: binding to the mRNA in the presence of tryptophan, this results in transcription termination [http://www.ncbi.nlm.nih.gov/sites/entrez/8419914 PubMed]
  
 
* '''Additional information:'''
 
* '''Additional information:'''
Line 120: Line 120:
 
=References=
 
=References=
  
<pubmed> 14976255, 3924737, 6436812  </pubmed>
+
<pubmed> 14976255, 3924737, 6436812,2422155,8419914, 1551827 </pubmed>
 
# Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed]
 
# Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed]

Revision as of 17:41, 27 May 2009

  • Description: indole-3-glycerol-phosphate synthase

Gene name trpC
Synonyms
Essential no
Product indole-3-glycerol-phosphate synthase
Function biosynthesis of tryptophan
MW, pI 27 kDa, 5.535
Gene length, protein length 750 bp, 250 aa
Immediate neighbours trpF, trpD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
TrpC context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O (according to Swiss-Prot)
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:

Additional information

Expression and regulation

  • Regulatory mechanism: TRAP: binding to the mRNA in the presence of tryptophan, this results in transcription termination PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed