Transcription factors modulated by trigger enzymes

The activity of these transcription factors is controlled by either modification by or regulatory interaction with trigger enzymes in response to specific signals (usually nutrient availability).

Transcription factors controlled by trigger enzyme-dependent covalent modification

• GlcT: controlled by PtsG
• LicT: controlled by BglP
• SacT: controlled by SacP
• SacY: controlled by SacX
• LevR: controlled by LevE
• LicR: controlled by LicB
• ManR: controlled by ManP
• MtlR: controlled by MtlA

Transcription factors controlled by regulatory interactions with a trigger enzyme

** The interaction results in loss of DNA-binding activity of the transcription factor

• GltC: controlled by RocG or GudB (the latter in non-domesticated strains)
• TnrA: controlled by GlnA

** The interaction results in gain of DNA-binding activity of the transcription factor

• GlnR: GlnA acts as co-repressor
• CymR: CysK acts as co-repressor