Transcription factors activating transcription at SigL-dependent promoters

These transcription factors activate transcription at SigL-dependent promoters. RNA polymerase containing SigL is inactive unless productive interaction with an activator protein occurs. Therefore, SigL-dependent genes are among the most strongly regulated genes in B. subtilis.

Activators controlled by interaction with low molecular weight effectors

• AcoR: control of acetoin utilization (acoA-acoB-acoC-acoL)
• BkdR: control of the utilization of branched chain amino acids
• RocR: control of the utilization of arginine, ornithine and citrulline (rocA-rocB-rocC, rocD-rocE-rocF, rocG)

Activator controlled by PTS-dependent phosphorylation

• LevR: control of fructose utilization (levD-levE-levF-levG-sacC)

Unknown activator

• YplP: required for growth at low temperatures

Reviews

L Lauren Beck, Todd G Smith, Timothy R Hoover
Look, no hands! Unconventional transcriptional activators in bacteria.
Trends Microbiol: 2007, 15(12);530-7
[PubMed:17997097] [WorldCat.org] [DOI] (P p)