Difference between revisions of "ThrC"

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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[thrB]]'', ''[[hom]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[thrB]]'', ''[[hom]]''
 
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU32250 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU32250 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU32250 Advanced_DNA]
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU32250 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU32250 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU32250 DNA_with_flanks]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:thrC_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:thrC_context.gif]]

Revision as of 11:11, 14 May 2013

  • Description: threonine synthase

Gene name thrC
Synonyms thrB
Essential no
Product threonine synthase
Function biosynthesis of threonine
Gene expression levels in SubtiExpress: thrC
Metabolic function and regulation of this protein in SubtiPathways:
Lys, Thr
MW, pI 37 kDa, 5.185
Gene length, protein length 1056 bp, 352 aa
Immediate neighbours thrB, hom
Sequences Protein DNA DNA_with_flanks
Genetic context
ThrC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
ThrC expression.png




























Categories containing this gene/protein

biosynthesis/ acquisition of amino acids

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU32250

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: O-phospho-L-homoserine + H2O = L-threonine + phosphate (according to Swiss-Prot)
  • Protein family: serine/threonine dehydratase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 1UIN (from Thermus thermophilus, 51% identity, 69% similarity) PubMed
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
    • repressed by casamino acids PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References