Difference between revisions of "ThiC"

From SubtiWiki
Jump to: navigation, search
Line 82: Line 82:
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P45740 P45740]
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P45740 P45740]
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU08790]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU08790 BSU08790]
  
 
* '''E.C. number:'''
 
* '''E.C. number:'''

Revision as of 00:19, 14 May 2009

  • Description: biosynthesis of the pyrimidine moiety of thiamine

Gene name thiC
Synonyms thiA
Essential no
Product unknown
Function biosynthesis of thiamine
MW, pI 65 kDa, 5.262
Gene length, protein length 1770 bp, 590 aa
Immediate neighbours ygaJ, ygaK
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
ThiC context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: thiC family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • E.C. number:

Additional information

  • subject to Clp-dependent proteolysis upon glucose starvation PubMed

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information: subject to Clp-dependent proteolysis upon glucose starvation PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Gerth et al. (2008) Clp-dependent proteolysis down-regulates central metabolic pathways in glucose-starved Bacillus subtilis. J Bacteriol 190:321-331 PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed