TagH

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  • Description: ABC transporter for teichoic acid translocation (ATP-binding protein)

Gene name tagH
Synonyms
Essential yes PubMed
Product ABC transporter for teichoic acid translocation (ATP-binding protein)
Function biosynthesis of teichoic acid
Gene expression levels in SubtiExpress: tagH
Interactions involving this protein in SubtInteract: TagH
Metabolic function and regulation of this protein in SubtiPathways:
TagH
MW, pI 59 kDa, 9.447
Gene length, protein length 1581 bp, 527 aa
Immediate neighbours yvzE, tagG
Sequences Protein DNA DNA_with_flanks
Genetic context
TagH context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
TagH expression.png

























Categories containing this gene/protein

cell wall synthesis, ABC transporters, biosynthesis of cell wall components, essential genes, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU35700

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + H2O + teichoic acid(In) = ADP + phosphate + teichoic acid(Out) (according to Swiss-Prot)
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Kathrin Schirner, Laura K Stone, Suzanne Walker
ABC transporters required for export of wall teichoic acids do not discriminate between different main chain polymers.
ACS Chem Biol: 2011, 6(5);407-12
[PubMed:21280653] [WorldCat.org] [DOI] (I p)

Alex Formstone, Rut Carballido-López, Philippe Noirot, Jeffery Errington, Dirk-Jan Scheffers
Localization and interactions of teichoic acid synthetic enzymes in Bacillus subtilis.
J Bacteriol: 2008, 190(5);1812-21
[PubMed:18156271] [WorldCat.org] [DOI] (I p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)

V Lazarevic, D Karamata
The tagGH operon of Bacillus subtilis 168 encodes a two-component ABC transporter involved in the metabolism of two wall teichoic acids.
Mol Microbiol: 1995, 16(2);345-55
[PubMed:7565096] [WorldCat.org] [DOI] (P p)