tagH

168

[wiki|ABC transporter] for teichoic acid translocation (ATP-binding protein)

locus: BSU_35700

Molecular weight: 59.07 kDa

pI: 9.45

Protein length: 527 aa

Gene length: 1584 bp

function: [category|SW.2.6.1.3|Biosynthesis of teichoic acid]

product: [wiki|ABC transporter] for teichoic acid translocation (ATP-binding protein)

essential: yes

ec: 3.6.3.40

synonyms: tagH

List of homologs in different organisms, belongs to COG1134 (Galperin et al., 2021)

Gene

Coordinates: 3,673,564  3,675,147

Phenotypes of a mutant

• essential [Pubmed|12682299]

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The protein

Catalyzed reaction/ biological activity

• ATP + H₂O + teichoic acid(Side 1) --> ADP + phosphate + teichoic acid(Side 2) (according to UniProt)

Protein family

• [wiki|ABC transporter superfamily] (according to UniProt)

[wiki|Domains]

• [wiki|ABC transporter domain] (aa 5-242) (according to UniProt)

Structure

• [PDB|6JBH] (the complex corresponding to [protein|6795F1703416DCD04E51C177F1C9FE45E73ABAEF|tagG]-[protein|4D3C316965834130BB378CBD1265CFA13F086C7A|tagH] from Alicyclobacillus herbarius, corresponds to aa 1 ... 262, 54.4% identity) [pubmed|32184247]
• [AF|P42954]

[wiki|Localization]

• membrane associated (via [protein|6795F1703416DCD04E51C177F1C9FE45E73ABAEF|tagG]) [Pubmed|10092453]

Biological materials

GFP fusion

• 3110 [gene|0467447B10EE7C1FDF86022AB6FBDBABFD32A9E5|trpC]2 [gene|4D3C316965834130BB378CBD1265CFA13F086C7A|tagH]::pSG5050 (cat P_xyl-gfp-[gene|4D3C316965834130BB378CBD1265CFA13F086C7A|tagH]1-648) [pubmed|18156271], available in [wiki|Dirk Jan Scheffers]' lab and in the [http://bgsc.org BGSC]

References

Reviews

• 24024634

Original Publications

• 36815589,18156271,10092453,7565096,21280653,22383849,29877791,32184247