Difference between revisions of "TagH"
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Revision as of 15:43, 16 May 2013
- Description: ABC transporter for teichoic acid translocation (ATP-binding protein)
| Gene name | tagH |
| Synonyms | |
| Essential | yes PubMed |
| Product | ABC transporter for teichoic acid translocation (ATP-binding protein) |
| Function | biosynthesis of teichoic acid |
| Gene expression levels in SubtiExpress: tagH | |
| Interactions involving this protein in SubtInteract: TagH | |
| MW, pI | 59 kDa, 9.447 |
| Gene length, protein length | 1581 bp, 527 aa |
| Immediate neighbours | yvzE, tagG |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
cell wall synthesis, ABC transporters, biosynthesis of cell wall components, essential genes, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU35700
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + H2O + teichoic acid(In) = ADP + phosphate + teichoic acid(Out) (according to Swiss-Prot)
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: membrane associated (via TagG) PubMed
Database entries
- Structure:
- UniProt: P42954
- KEGG entry: [2]
- E.C. number: 3.6.3.40
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Kathrin Schirner, Laura K Stone, Suzanne Walker
ABC transporters required for export of wall teichoic acids do not discriminate between different main chain polymers.
ACS Chem Biol: 2011, 6(5);407-12
[PubMed:21280653]
[WorldCat.org]
[DOI]
(I p)
Alex Formstone, Rut Carballido-López, Philippe Noirot, Jeffery Errington, Dirk-Jan Scheffers
Localization and interactions of teichoic acid synthetic enzymes in Bacillus subtilis.
J Bacteriol: 2008, 190(5);1812-21
[PubMed:18156271]
[WorldCat.org]
[DOI]
(I p)
Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453]
[WorldCat.org]
[DOI]
(P p)
V Lazarevic, D Karamata
The tagGH operon of Bacillus subtilis 168 encodes a two-component ABC transporter involved in the metabolism of two wall teichoic acids.
Mol Microbiol: 1995, 16(2);345-55
[PubMed:7565096]
[WorldCat.org]
[DOI]
(P p)
