Difference between revisions of "SufB"

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|style="background:#ABCDEF;" align="center"|'''Function''' || synthesis of iron-sulfur clusters
 
|style="background:#ABCDEF;" align="center"|'''Function''' || synthesis of iron-sulfur clusters
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU32670 sufB]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU32670 sufB]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 52 kDa, 4.958   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 52 kDa, 4.958   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yuzN]]'', ''[[sufU]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yuzN]]'', ''[[sufU]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15256&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU32670 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU32670 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU32670 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:yurU_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yurU_context.gif]]

Revision as of 13:47, 13 May 2013

  • Description: synthesis of Fe-S-clusters

Gene name sufB
Synonyms yurU
Essential yes PubMed
Product unknown
Function synthesis of iron-sulfur clusters
Gene expression levels in SubtiExpress: sufB
MW, pI 52 kDa, 4.958
Gene length, protein length 1395 bp, 465 aa
Immediate neighbours yuzN, sufU
Sequences Protein DNA Advanced_DNA
Genetic context
YurU context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SufB expression.png
























Categories containing this gene/protein

iron metabolism, essential genes

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU32670

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

  • subject to Clp-dependent proteolysis upon glucose starvation PubMed

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information: subject to Clp-dependent proteolysis upon glucose starvation PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Alexander G Albrecht, Daili J A Netz, Marcus Miethke, Antonio J Pierik, Olaf Burghaus, Florian Peuckert, Roland Lill, Mohamed A Marahiel
SufU is an essential iron-sulfur cluster scaffold protein in Bacillus subtilis.
J Bacteriol: 2010, 192(6);1643-51
[PubMed:20097860] [WorldCat.org] [DOI] (I p)

Ulf Gerth, Holger Kock, Ilja Kusters, Stephan Michalik, Robert L Switzer, Michael Hecker
Clp-dependent proteolysis down-regulates central metabolic pathways in glucose-starved Bacillus subtilis.
J Bacteriol: 2008, 190(1);321-31
[PubMed:17981983] [WorldCat.org] [DOI] (I p)