SufA

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  • Description: iron-sulfur cluster scaffold protein

Gene name sufA
Synonyms yutM
Essential no
Product iron-sulfur cluster scaffold protein
Function assembly of Fe-S clusters
Gene expression levels in SubtiExpress: sufA
MW, pI 12 kDa, 4.52
Gene length, protein length 360 bp, 120 aa
Immediate neighbours paiA, dapF
Sequences Protein DNA DNA_with_flanks
Genetic context
YutM context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SufA expression.png
























Categories containing this gene/protein

iron metabolism

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU32160

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: hesB/iscA family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Alexander G Albrecht, Daili J A Netz, Marcus Miethke, Antonio J Pierik, Olaf Burghaus, Florian Peuckert, Roland Lill, Mohamed A Marahiel
SufU is an essential iron-sulfur cluster scaffold protein in Bacillus subtilis.
J Bacteriol: 2010, 192(6);1643-51
[PubMed:20097860] [WorldCat.org] [DOI] (I p)

Patrick W Bilder, Huangen Ding, Marcia E Newcomer
Crystal structure of the ancient, Fe-S scaffold IscA reveals a novel protein fold.
Biochemistry: 2004, 43(1);133-9
[PubMed:14705938] [WorldCat.org] [DOI] (P p)