Difference between revisions of "SubtiPathways"

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(Publications describing SubtiWiki and SubtiPathways)
 
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== Carbon metabolism ==
 
== Carbon metabolism ==
  
=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=cent Central carbon metabolism] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=7FvYw Central carbon metabolism] ===
  
=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=carb Utilization of different carbon sources] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=ps3UM Utilization of different carbon sources] ===
  
 
<br/>
 
<br/>
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== Nitrogen and amino acid metabolism ==
 
== Nitrogen and amino acid metabolism ==
  
=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=glut Ammonium assimilation and glutamate metabolism (incl. glutamine and arginine)] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=Cog2y Ammonium assimilation and glutamate metabolism (incl. glutamine and arginine)] ===
  
=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=alan Alanine, glycine, serine] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=mONyM Alanine, glycine, serine] ===
  
=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=aspa Aspartate, asparagine] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=81K4b Aspartate, asparagine] ===
  
=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=cyst Cysteine, methionine] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=1Jfrj Cysteine, methionine] ===
  
=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=hist Histidine] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=DNohR Histidine] ===
  
=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=isol Isoleucine, valine, leucine] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=V2MSg Isoleucine, valine, leucine] ===
  
 
=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=lysi Lysine, threonine] ===
 
=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=lysi Lysine, threonine] ===
  
=== [http://subtiwiki.uni-goettingen.de/pathways/phenyl_tyr_tryp.html Phenylalanine, tyrosine, tryptophan] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=qSUN0 Phenylalanine, tyrosine, tryptophan] ===
  
=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=prol Proline] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=bM03y Proline] ===
  
=== [http://subtiwiki.uni-goettingen.de/pathways/other_nitrogen_sources/index.html Utilization of other nitrogen sources] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=JKtpr Utilization of other nitrogen sources] ===
  
 
<br/>
 
<br/>
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== Lipid metabolism ==
 
== Lipid metabolism ==
  
=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=fatt Fatty acid and phospholipid biosynthesis] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=fatt Fatty acid metabolism] ===
  
=== [http://subtiwiki.uni-goettingen.de/pathways/fatty_acid_degradation.html Fatty acid degradation] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=cnliR Fatty acid and phospholipid biosynthesis] ===
  
 
<br/>
 
<br/>
  
 
== Nucleotides ==
 
== Nucleotides ==
 
=== [http://subtiwiki.uni-goettingen.de/pathways/gene_regulation_nucleotides.html Gene regulation of nucleotide metabolism] ===
 
  
 
=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=nucl Nucleoside catabolism] ===
 
=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=nucl Nucleoside catabolism] ===
  
=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=meta Purine biosynthesis] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=etxDX Purine biosynthesis] ===
  
=== [http://subtiwiki.uni-goettingen.de/pathways/purines_catabolism.html Purine catabolism] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=bxwTq Purine catabolism] ===
  
 
=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=puri Purine salvage pathways] ===
 
=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=puri Purine salvage pathways] ===
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== Metabolism of cofactors ==
 
== Metabolism of cofactors ==
  
=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=synt CoA synthesis] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=cUo5h CoA synthesis] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=faSwm Folate biosynthesis] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=2GTKN Menaquinone] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=4Ww0E Riboflavin and FAD synthesis] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=wTyck Thiamin synthesis] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=8iQpH Biotin synthesis] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=op4I3 Heme biosynthesis] ===
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===[http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=wAgIW Molybdopterin synthesis] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=3vSpz NAD synthesis] ===
  
=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=fola Folate biosynthesis] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=Zjt4G Lipoate synthesis] ===
  
=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=mena Menaquinone] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=moarx Pyridoxalphospahte synthesis] ===
  
=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=ribo Riboflavin and FAD synthesis] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=AwkEg S-adenosylmethionine synthesis] ===
  
=== [http://subtiwiki.uni-goettingen.de/pathways/thiamin.html Thiamin synthesis] ===
 
  
=== [http://subtiwiki.uni-goettingen.de/pathways/biotin/index.html Biotin synthesis] ===
 
  
 
<br/>
 
<br/>
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== Other pathways ==
 
== Other pathways ==
  
=== [http://subtiwiki.uni-goettingen.de/pathways/cellwall.html Cell wall] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=LlfNo Peptidoglycan synthesis] [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=RqnXf Peptidoglycan catabolism] [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=aARFz Teichonic acid] ===
 
 
=== [http://subtiwiki.uni-goettingen.de/pathways/murein/index.html Murein recycling] ===
 
  
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=RDamU ppGpp] [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=Tvl8u cdAMP] [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=E6M7Y cdGMP] ===
 
=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=stre Stress responses] ===
 
=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=stre Stress responses] ===
  
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=trna tRNA charging] ===
 
=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=trna tRNA charging] ===
  
=== [http://subtiwiki.uni-goettingen.de/pathways/biofilm.html Biofilm formation] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=BPSRv Biofilm formation] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=95Yqn Protein secretion] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=V1JFH Acquisition of iron ] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=LNqKW Metal ion homeostasis] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=pM5k3 Trace metal homeostasis] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=4FfA6 Amino acids transporter] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=KheJp Bactoprenol synthesis] ===
  
=== [http://subtiwiki.uni-goettingen.de/pathways/secretion/index.html Protein secretion] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=SO2Za Methylglyoxal pathway] ===
  
=== [http://cellpublisher.gobics.de/view/GqbblRJkBH metal ion homeostasis] ===
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=== [http://subtiwiki.uni-goettingen.de/subtipathways/index.php?pathway=YDHgj Respiration] ===
  
 
== Publications describing ''Subti''Wiki and ''Subti''Pathways ==
 
== Publications describing ''Subti''Wiki and ''Subti''Pathways ==
<pubmed>19959575 22096228</pubmed>
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<pubmed>19959575 22096228     24178028</pubmed>

Latest revision as of 08:15, 13 May 2014

Pathway start page small.png
legend for SubtiPathways
graphical notation: click to enlarge

SubtiPathways is a model of B. subtilis metabolism and regulation in SBML/SBGN (Systems Biology Markup Language/ Graphical Notation). There is a color code for key metabolites (see the legend on the right side).

It can be used like Google Maps (scroll and zoom to the pathways). The markers of proteins and compounds listed on the right side in each pathway are containing links to the corresponding SubtiWiki and PubChem pages, respectively. There is a short description for each protein in the bubbles, too.

Contact: General Microbiology, University of Göttingen, send mail


Now online: A description of SubtiWiki, SubtiPathways, and SubtInteract in the 2012 Database issue of Nucleic Acids Research

Ulrike Mäder, Arne G Schmeisky, Lope A Flórez, Jörg Stülke
SubtiWiki--a comprehensive community resource for the model organism Bacillus subtilis.
Nucleic Acids Res: 2012, 40(Database issue);D1278-87
[PubMed:22096228] [WorldCat.org] [DOI] (I p)



A collection of important papers on B. subtilis metabolism can be found here


Carbon metabolism

Central carbon metabolism

Utilization of different carbon sources


Nitrogen and amino acid metabolism

Ammonium assimilation and glutamate metabolism (incl. glutamine and arginine)

Alanine, glycine, serine

Aspartate, asparagine

Cysteine, methionine

Histidine

Isoleucine, valine, leucine

Lysine, threonine

Phenylalanine, tyrosine, tryptophan

Proline

Utilization of other nitrogen sources


Lipid metabolism

Fatty acid metabolism

Fatty acid and phospholipid biosynthesis


Nucleotides

Nucleoside catabolism

Purine biosynthesis

Purine catabolism

Purine salvage pathways

Pyrimidine metabolism


Metabolism of cofactors

CoA synthesis

Folate biosynthesis

Menaquinone

Riboflavin and FAD synthesis

Thiamin synthesis

Biotin synthesis

Heme biosynthesis

Molybdopterin synthesis

NAD synthesis

Lipoate synthesis

Pyridoxalphospahte synthesis

S-adenosylmethionine synthesis


Other pathways

Peptidoglycan synthesis Peptidoglycan catabolism Teichonic acid

ppGpp cdAMP cdGMP

Stress responses

Phosphorelay

Sulfate assimilation

tRNA charging

Biofilm formation

Protein secretion

Acquisition of iron

Metal ion homeostasis

Trace metal homeostasis

Amino acids transporter

Bactoprenol synthesis

Methylglyoxal pathway

Respiration

Publications describing SubtiWiki and SubtiPathways

Raphael H Michna, Fabian M Commichau, Dominik Tödter, Christopher P Zschiedrich, Jörg Stülke
SubtiWiki-a database for the model organism Bacillus subtilis that links pathway, interaction and expression information.
Nucleic Acids Res: 2014, 42(Database issue);D692-8
[PubMed:24178028] [WorldCat.org] [DOI] (I p)

Ulrike Mäder, Arne G Schmeisky, Lope A Flórez, Jörg Stülke
SubtiWiki--a comprehensive community resource for the model organism Bacillus subtilis.
Nucleic Acids Res: 2012, 40(Database issue);D1278-87
[PubMed:22096228] [WorldCat.org] [DOI] (I p)

Christoph R Lammers, Lope A Flórez, Arne G Schmeisky, Sebastian F Roppel, Ulrike Mäder, Leendert Hamoen, Jörg Stülke
Connecting parts with processes: SubtiWiki and SubtiPathways integrate gene and pathway annotation for Bacillus subtilis.
Microbiology (Reading): 2010, 156(Pt 3);849-859
[PubMed:19959575] [WorldCat.org] [DOI] (I p)