Difference between revisions of "SsuA"

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* '''Description:''' aliphatic sulfonate [[ABC transporter]] (binding lipoprotein) <br/><br/>
 
 
 
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Revision as of 08:39, 13 August 2012

Gene name ssuA
Synonyms ygbA, yzeA
Essential no
Product aliphatic sulfonate ABC transporter (binding lipoprotein)
Function sulfonate uptake
Gene expression levels in SubtiExpress: ssuA
Interactions involving this protein in SubtInteract: SsuA
Metabolic function and regulation of this protein in SubtiPathways:
Cys, Met & Sulfate assimilation
MW, pI 36 kDa, 4.85
Gene length, protein length 996 bp, 332 aa
Immediate neighbours ssuB, ssuC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SsuA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SsuA expression.png




























Categories containing this gene/protein

ABC transporters, sulfur metabolism, membrane proteins

This gene is a member of the following regulons

CymR regulon

The gene

Basic information

  • Locus tag: BSU08840

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: bacterial solute-binding protein ssuA/tauA family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed in the presence of cysteine (CymR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Sergine Even, Pierre Burguière, Sandrine Auger, Olga Soutourina, Antoine Danchin, Isabelle Martin-Verstraete
Global control of cysteine metabolism by CymR in Bacillus subtilis.
J Bacteriol: 2006, 188(6);2184-97
[PubMed:16513748] [WorldCat.org] [DOI] (P p)

Kyle N Erwin, Shunji Nakano, Peter Zuber
Sulfate-dependent repression of genes that function in organosulfur metabolism in Bacillus subtilis requires Spx.
J Bacteriol: 2005, 187(12);4042-9
[PubMed:15937167] [WorldCat.org] [DOI] (P p)

J R van der Ploeg, M Barone, T Leisinger
Expression of the Bacillus subtilis sulphonate-sulphur utilization genes is regulated at the levels of transcription initiation and termination.
Mol Microbiol: 2001, 39(5);1356-65
[PubMed:11251850] [WorldCat.org] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)

Jan R van der Ploeg, Nicola J Cummings, Thomas Leisinger, Ian F Connerton
Bacillus subtilis genes for the utilization of sulfur from aliphatic sulfonates.
Microbiology (Reading): 1998, 144 ( Pt 9);2555-2561
[PubMed:9782504] [WorldCat.org] [DOI] (P p)