Difference between revisions of "SsuA"

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|style="background:#ABCDEF;" align="center"|'''Function''' || sulfonate uptake
 
|style="background:#ABCDEF;" align="center"|'''Function''' || sulfonate uptake
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU08840 ssuA]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU08840 ssuA]
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SsuA SsuA]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SsuA SsuA]
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ssuB]]'', ''[[ssuC]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ssuB]]'', ''[[ssuC]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12712&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU08840 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU08840 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU08840 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:ssuA_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ssuA_context.gif]]

Revision as of 12:24, 13 May 2013

Gene name ssuA
Synonyms ygbA, yzeA
Essential no
Product aliphatic sulfonate ABC transporter (binding lipoprotein)
Function sulfonate uptake
Gene expression levels in SubtiExpress: ssuA
Interactions involving this protein in SubtInteract: SsuA
Metabolic function and regulation of this protein in SubtiPathways:
Cys, Met & Sulfate assimilation
MW, pI 36 kDa, 4.85
Gene length, protein length 996 bp, 332 aa
Immediate neighbours ssuB, ssuC
Sequences Protein DNA Advanced_DNA
Genetic context
SsuA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SsuA expression.png




























Categories containing this gene/protein

ABC transporters, sulfur metabolism, membrane proteins

This gene is a member of the following regulons

CymR regulon

The gene

Basic information

  • Locus tag: BSU08840

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: bacterial solute-binding protein ssuA/tauA family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed in the presence of cysteine (CymR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Sergine Even, Pierre Burguière, Sandrine Auger, Olga Soutourina, Antoine Danchin, Isabelle Martin-Verstraete
Global control of cysteine metabolism by CymR in Bacillus subtilis.
J Bacteriol: 2006, 188(6);2184-97
[PubMed:16513748] [WorldCat.org] [DOI] (P p)

Kyle N Erwin, Shunji Nakano, Peter Zuber
Sulfate-dependent repression of genes that function in organosulfur metabolism in Bacillus subtilis requires Spx.
J Bacteriol: 2005, 187(12);4042-9
[PubMed:15937167] [WorldCat.org] [DOI] (P p)

J R van der Ploeg, M Barone, T Leisinger
Expression of the Bacillus subtilis sulphonate-sulphur utilization genes is regulated at the levels of transcription initiation and termination.
Mol Microbiol: 2001, 39(5);1356-65
[PubMed:11251850] [WorldCat.org] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)

Jan R van der Ploeg, Nicola J Cummings, Thomas Leisinger, Ian F Connerton
Bacillus subtilis genes for the utilization of sulfur from aliphatic sulfonates.
Microbiology (Reading): 1998, 144 ( Pt 9);2555-2561
[PubMed:9782504] [WorldCat.org] [DOI] (P p)