Difference between revisions of "SpsK"
| Line 56: | Line 56: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU37820&redirect=T BSU37820] | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/sps.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/sps.html] | ||
| Line 93: | Line 94: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU37820&redirect=T BSU37820] | ||
* '''Structure:''' [http://www.pdb.org/pdb/explore/explore.do?structureId=3SC6 3SC6] (dTDP-4-dehydrorhamnose reductase (''rfbD'') from ''Bacillus anthracis'' str. Ames in complex with NADP; 42% identity, 72% similarity) | * '''Structure:''' [http://www.pdb.org/pdb/explore/explore.do?structureId=3SC6 3SC6] (dTDP-4-dehydrorhamnose reductase (''rfbD'') from ''Bacillus anthracis'' str. Ames in complex with NADP; 42% identity, 72% similarity) | ||
Revision as of 16:06, 2 April 2014
- Description: dTDP -4-dehydrorhamnose reductase, spore coat polysaccharide synthesis
| Gene name | spsK |
| Synonyms | ipa-73d |
| Essential | no |
| Product | dTDP -4-dehydrorhamnose reductase |
| Function | rhamnose biosynthesis, spore coat polysaccharide synthesis |
| Gene expression levels in SubtiExpress: spsK | |
| MW, pI | 31 kDa, 6.081 |
| Gene length, protein length | 849 bp, 283 aa |
| Immediate neighbours | spsL, spsJ |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
miscellaneous metabolic pathways, sporulation proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU37820
Phenotypes of a mutant
Database entries
- BsubCyc: BSU37820
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: dTDP-4-dehydrorhamnose reductase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- BsubCyc: BSU37820
- Structure: 3SC6 (dTDP-4-dehydrorhamnose reductase (rfbD) from Bacillus anthracis str. Ames in complex with NADP; 42% identity, 72% similarity)
- UniProt: P39631
- KEGG entry: [3]
- E.C. number: 1.1.1.133
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Germán Plata, Tobias Fuhrer, Tzu-Lin Hsiao, Uwe Sauer, Dennis Vitkup
Global probabilistic annotation of metabolic networks enables enzyme discovery.
Nat Chem Biol: 2012, 8(10);848-54
[PubMed:22960854]
[WorldCat.org]
[DOI]
(I p)
Patrick Eichenberger, Masaya Fujita, Shane T Jensen, Erin M Conlon, David Z Rudner, Stephanie T Wang, Caitlin Ferguson, Koki Haga, Tsutomu Sato, Jun S Liu, Richard Losick
The program of gene transcription for a single differentiating cell type during sporulation in Bacillus subtilis.
PLoS Biol: 2004, 2(10);e328
[PubMed:15383836]
[WorldCat.org]
[DOI]
(I p)
E Presecan, I Moszer, L Boursier, H Cruz Ramos, V de la Fuente, M-F Hullo, C Lelong, S Schleich, A Sekowska, B H Song, G Villani, F Kunst, A Danchin, P Glaser
The Bacillus subtilis genome from gerBC (311 degrees) to licR (334 degrees).
Microbiology (Reading): 1997, 143 ( Pt 10);3313-3328
[PubMed:9353933]
[WorldCat.org]
[DOI]
(P p)
