spsD

168

legionaminic acid synthesis

locus: BSU_37880

Molecular weight: 32.99 kDa

pI: 6

Protein length: 289 aa

Gene length: 870 bp

function: legionaminic acid synthesis

product: unknown

essential: no

synonyms: spsD, ipa-66d

List of homologs in different organisms, belongs to COG1670 (Galperin et al., 2021)

Gene

Coordinates: 3,888,862  3,889,731

Phenotypes of a mutant

• the mutant tends to acquire suppressor mutations that result in improved growth [Pubmed|28189581]
• less hydrophobic spore surface [pubmed|32817102]

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The protein

Catalyzed reaction/ biological activity

• required for spore crust assembly, legionaminic acid synthesis [pubmed|32817102]

[wiki|Domains]

• [wiki|N-acetyltransferase domain] (aa 137-289) (according to UniProt)

Structure

• [AF|P39624]

Biological materials

Mutant

• BKE37880 ([gene|2648D9E356683F5E9C00C40F0A6BBD1933322B09|spsD]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE37880 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_GACATTTTCTTTTACCGTAT,  downstream forward: _UP4_TGGCCGGGCAAGGAGGCGAA
• BKK37880 ([gene|2648D9E356683F5E9C00C40F0A6BBD1933322B09|spsD]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK37880 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_GACATTTTCTTTTACCGTAT,  downstream forward: _UP4_TGGCCGGGCAAGGAGGCGAA

References

• 9353933,15383836,25239894,26577401,32817102