SpoVT

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  • Description: transcription activator and repressor of SigG-dependent genes

Gene name spoVT
Synonyms yabL
Essential no
Product transcriptional regulator
Function regulation of forespore gene expression
MW, pI 19 kDa, 4.676
Gene length, protein length 534 bp, 178 aa
Immediate neighbours mfd, yabM
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SpoVT context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s): AbrB, Abh (only the N-terminal domains (aa 1 through 50) are conserved between SpoVT and the two paralogues)

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: Cytoplasm (Homogeneous) PubMed

Database entries

  • Structure: 2W1R (full-length), 2W1T (C-terminal domain)
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Meile et al. (2006) Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory Proteomics 6: 2135-2146. PubMed
  2. Yao, F and M.A. Strauch (2005) Independent and Interchangeable Multimerization Domains of the AbrB, Abh and SpoVT Global Regulatory Proteins. J. Bacteriol. 187:6354-6362 PubMed
  3. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed