SpoVT

• Description: transcription activator and repressor of SigG-dependent genes
  
  

Gene name	spoVT
Synonyms	yabL
Essential	no
Product	transcriptional regulator
Function	regulation of forespore gene expression
Metabolic function and regulation of this protein in SubtiPathways: Lys, Thr, Stress
MW, pI	19 kDa, 4.676
Gene length, protein length	534 bp, 178 aa
Immediate neighbours	mfd, yabM
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription factors and their control, sporulation proteins

This gene is a member of the following regulons

SigF regulon, SigG regulon

The gene

Basic information

• Locus tag: BSU00560

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): AbrB, Abh (only the N-terminal domains (aa 1 through 50) are conserved between SpoVT and the two paralogues)

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: Cytoplasm (Homogeneous) PubMed

Database entries

• Structure: 2W1R (full-length), 2W1T (C-terminal domain)

• UniProt: P37554

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: spoVT PubMed

• Expression browser: spoVT PubMed

• Sigma factor: SigF PubMed, SigG PubMed

• Regulation: expressed in the forespore (SigG) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Arturo Ramirez-Peralta, Kerry-Ann V Stewart, Stacy K Thomas, Barbara Setlow, Zhan Chen, Yong-qing Li, Peter Setlow
Effects of the SpoVT regulatory protein on the germination and germination protein levels of spores of Bacillus subtilis.
J Bacteriol: 2012, 194(13);3417-25
[PubMed:22522895] [WorldCat.org] [DOI] (I p)