spoVT

168

transcription activator and repressor of [protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG]-dependent genes

locus: BSU_00560

Molecular weight: 19.60 kDa

pI: 4.68

Protein length: 178 aa

Gene length: 537 bp

function: regulation of forespore gene expression

product: transcriptional regulator

essential: no

synonyms: spoVT, yabL

List of homologs in different organisms, belongs to COG5845 (Galperin et al., 2021)

Gene

Coordinates: 64,099 64,635

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The protein

[wiki|Domains]

• [wiki|SpoVT-AbrB domain] (aa 5-51) (according to UniProt)

Structure

• [PDB|2W1R] (full-length), [PDB|2W1T] (C-terminal domain) [PDB|2RO5] (recognition domain)
• [AF|P37554]

Paralogous protein(s)

• [protein|E5110D9C36E8C55AFD1419987B14A53232165F20|abrB]
• [protein|5872812AB61E92E2944E926915EB7FEE71BFA6D5|abh], (only the N-terminal domains (aa 1 through 50) are conserved between SpoVT and the two paralogues)

[wiki|Localization]

• Cytoplasm (Homogeneous) [Pubmed|16479537]

Biological materials

Mutant

• BKE00560 ([gene|01EF886D3D004EA9B22AC5E75D50FF07D8631E68|spoVT]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE00560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTCTGGTGCCTCTCTTT, downstream forward: _UP4_TAGGTCTTATTCCTTTCTTC
• BKK00560 ([gene|01EF886D3D004EA9B22AC5E75D50FF07D8631E68|spoVT]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK00560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTCTGGTGCCTCTCTTT, downstream forward: _UP4_TAGGTCTTATTCCTTTCTTC

References

Reviews

• 31350897,35638784

Original Publications

• 16497325,18996130,15063493,8755877,16479537,16159768,22522895,15980461,27790204