SpoVS

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  • Description: required for dehydratation of the spore core and assembly of the coat, mutation increases SigD-dependent gene expression, might act via SinR

Gene name spoVS
Synonyms
Essential no
Product unknown
Function spore coat assembly, spore core dehydratation
MW, pI 8 kDa, 6.475
Gene length, protein length 258 bp, 86 aa
Immediate neighbours ymdB, tdh
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SpoVS context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

sporulation/ other

This gene is a member of the following regulons

SigH regulon

The gene

Basic information

  • Locus tag: BSU16980

Phenotypes of a mutant

increased SigD-dependent gene expression, this might occur via SinR PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed at the onset of stationary phase (SigH) PubMed
  • Regulatory mechanism:
  • Additional information:
    • The mRNA has a long 5' leader region. This may indicate RNA-based regulation PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system: B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in Stülke lab
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Irnov Irnov, Cynthia M Sharma, Jörg Vogel, Wade C Winkler
Identification of regulatory RNAs in Bacillus subtilis.
Nucleic Acids Res: 2010, 38(19);6637-51
[PubMed:20525796] [WorldCat.org] [DOI] (I p)

Daniel J Rigden, Michael Y Galperin
Sequence analysis of GerM and SpoVS, uncharacterized bacterial 'sporulation' proteins with widespread phylogenetic distribution.
Bioinformatics: 2008, 24(16);1793-7
[PubMed:18562273] [WorldCat.org] [DOI] (I p)

Ana R Perez, Angelica Abanes-De Mello, Kit Pogliano
Suppression of engulfment defects in bacillus subtilis by elevated expression of the motility regulon.
J Bacteriol: 2006, 188(3);1159-64
[PubMed:16428420] [WorldCat.org] [DOI] (P p)

O Resnekov, A Driks, R Losick
Identification and characterization of sporulation gene spoVS from Bacillus subtilis.
J Bacteriol: 1995, 177(19);5628-35
[PubMed:7559352] [WorldCat.org] [DOI] (P p)