Difference between revisions of "SpoVG"

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|style="background:#ABCDEF;" align="center"|'''Function''' || cell division, control of sporulation initiation
 
|style="background:#ABCDEF;" align="center"|'''Function''' || cell division, control of sporulation initiation
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU00490 spoVG]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU00490 spoVG]
 
|-
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 10 kDa, 5.11   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 10 kDa, 5.11   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yabJ]]'', ''[[gcaD]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yabJ]]'', ''[[gcaD]]''
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB11825&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU00490 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU00490 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU00490 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:spoVG_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:spoVG_context.gif]]

Revision as of 11:55, 13 May 2013

  • Description: negative effector of asymetric septation at the onset of sporulation

Gene name spoVG
Synonyms
Essential no
Product negative effector of asymetric septation
Function cell division, control of sporulation initiation
Gene expression levels in SubtiExpress: spoVG
MW, pI 10 kDa, 5.11
Gene length, protein length 291 bp, 97 aa
Immediate neighbours yabJ, gcaD
Sequences Protein DNA Advanced_DNA
Genetic context
SpoVG context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SpoVG expression.png


























Categories containing this gene/protein

cell division, sporulation/ other, phosphoproteins

This gene is a member of the following regulons

AbrB regulon, SigH regulon, SinR regulon

The gene

Basic information

  • Locus tag: BSU00490

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: spoVG family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylation on (Ser-66 OR Ser-67 OR Thr-68) PubMed
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

  • subject to Clp-dependent proteolysis upon glucose starvation PubMed

Expression and regulation

  • Additional information: subject to Clp-dependent proteolysis upon glucose starvation PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Hyun-Hwi Kim, Bong-Jin Lee, Ae-Ran Kwon
Expression, crystallization, and preliminary X-ray crystallographic analysis of putative SpoVG from Staphylococcus aureus.
Arch Pharm Res: 2010, 33(8);1285-8
[PubMed:20803133] [WorldCat.org] [DOI] (I p)

Boris Macek, Ivan Mijakovic, Jesper V Olsen, Florian Gnad, Chanchal Kumar, Peter R Jensen, Matthias Mann
The serine/threonine/tyrosine phosphoproteome of the model bacterium Bacillus subtilis.
Mol Cell Proteomics: 2007, 6(4);697-707
[PubMed:17218307] [WorldCat.org] [DOI] (P p)

Frances Chu, Daniel B Kearns, Steven S Branda, Roberto Kolter, Richard Losick
Targets of the master regulator of biofilm formation in Bacillus subtilis.
Mol Microbiol: 2006, 59(4);1216-28
[PubMed:16430695] [WorldCat.org] [DOI] (P p)

K Matsuno, A L Sonenshein
Role of SpoVG in asymmetric septation in Bacillus subtilis.
J Bacteriol: 1999, 181(11);3392-401
[PubMed:10348850] [WorldCat.org] [DOI] (P p)

O Resnekov, A Driks, R Losick
Identification and characterization of sporulation gene spoVS from Bacillus subtilis.
J Bacteriol: 1995, 177(19);5628-35
[PubMed:7559352] [WorldCat.org] [DOI] (P p)

P S Margolis, A Driks, R Losick
Sporulation gene spoIIB from Bacillus subtilis.
J Bacteriol: 1993, 175(2);528-40
[PubMed:8419299] [WorldCat.org] [DOI] (P p)

R Fürbass, M Gocht, P Zuber, M A Marahiel
Interaction of AbrB, a transcriptional regulator from Bacillus subtilis with the promoters of the transition state-activated genes tycA and spoVG.
Mol Gen Genet: 1991, 225(3);347-54
[PubMed:1850083] [WorldCat.org] [DOI] (P p)

P Zuber, R Losick
Role of AbrB in Spo0A- and Spo0B-dependent utilization of a sporulation promoter in Bacillus subtilis.
J Bacteriol: 1987, 169(5);2223-30
[PubMed:2437099] [WorldCat.org] [DOI] (P p)

M M Igo, R Losick
Regulation of a promoter that is utilized by minor forms of RNA polymerase holoenzyme in Bacillus subtilis.
J Mol Biol: 1986, 191(4);615-24
[PubMed:3100810] [WorldCat.org] [DOI] (P p)

C D Banner, C P Moran, R Losick
Deletion analysis of a complex promoter for a developmentally regulated gene from Bacillus subtilis.
J Mol Biol: 1983, 168(2);351-65
[PubMed:6411929] [WorldCat.org] [DOI] (P p)

W C Johnson, C P Moran, R Losick
Two RNA polymerase sigma factors from Bacillus subtilis discriminate between overlapping promoters for a developmentally regulated gene.
Nature: 1983, 302(5911);800-4
[PubMed:6405278] [WorldCat.org] [DOI] (P p)

J Segall, R Losick
Cloned Bacillus subtilis DNA containing a gene that is activated early during sporulation.
Cell: 1977, 11(4);751-61
[PubMed:408013] [WorldCat.org] [DOI] (P p)