spoVAEB

168

spore germinant protein, essential for the transport of the 1:1 chelate of pyridine-2,6-dicarboxylic acid (DPA(2,6)) and Ca(2+) into spores and DPA release during [category|SW.4.2.4|Germination]

locus: BSU_23402

Molecular weight: 12.00 kDa

pI: 6.25

Protein length: 116 aa

Gene length: 351 bp

function: spore germination

product: spore germinant protein

essential: no

ec: null

synonyms: spoVAEB

List of homologs in different organisms, belongs to COG5839 (Galperin et al., 2021)

Gene

Coordinates: 2,440,423  2,440,773

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The protein

Catalyzed reaction/ biological activity

• forms a membrane channel with [protein|B280951A232E941FB0A6C8834049765BE1E16437|spoVAC] [pubmed|35654455]

Structure

• [AF|C0H450]

[wiki|Localization]

• spore inner membrane, complex with [protein|B280951A232E941FB0A6C8834049765BE1E16437|spoVAC] and [protein|9531F0A0DC4AE5696FFBAC9C2A773F15840E3255|spoVAD] [pubmed|35654455]

Additional information

• stability in spores depends on [protein|B280951A232E941FB0A6C8834049765BE1E16437|spoVAC] [pubmed|35654455]

Biological materials

Mutant

• BKE23402 ([gene|31D6CB7EC20C39C1815CA4552B8B9C4BE304E86B|spoVAEB]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE23402 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_GACAAAAGCCAAAAGGTAGT,  downstream forward: _UP4_TTCAAACCGAAAGGATAATG
• BKK23402 ([gene|31D6CB7EC20C39C1815CA4552B8B9C4BE304E86B|spoVAEB]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK23402 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_GACAAAAGCCAAAAGGTAGT,  downstream forward: _UP4_TTCAAACCGAAAGGATAATG

labs

• [wiki|Peter Setlow], University of Connecticut Health Center, USA

References

Reviews

• 35638784

Original Publications

• 17573930,3114420,11751839,15451103,3926949,17158659,6432957,7934830,22328679,15699190,1903432,8755877,22343299,35654455