Difference between revisions of "SpoVAC"
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
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=Expression and regulation= | =Expression and regulation= | ||
− | * '''Operon:''' ''[[spoVAA]]-[[spoVAB]]-[[spoVAC]]-[[spoVAD]]-[[ | + | * '''Operon:''' ''[[spoVAA]]-[[spoVAB]]-[[spoVAC]]-[[spoVAD]]-[[spoVAEB]]-[[spoVAEA]]-[[spoVAF]]-[[lysA]]'' {{PubMed|7934830}} |
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoVAC_2441804_2442256_-1 spoVAC] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoVAC_2441804_2442256_-1 spoVAC] {{PubMed|22383849}} | ||
− | * '''Sigma factor:''' [[SigG]] {{PubMed|15699190,1903432}} | + | * '''[[Sigma factor]]:''' [[SigG]] {{PubMed|15699190,1903432}} |
* '''Regulation:''' | * '''Regulation:''' |
Revision as of 16:35, 25 January 2013
- Description: essential for the uptake of the 1:1 chelate of pyridine-2,6-dicarboxylic acid (DPA(2,6)) and Ca(2+) into developing spores, required for spore maturation
Gene name | spoVAC |
Synonyms | |
Essential | no |
Product | unknown |
Function | spore maturation |
Gene expression levels in SubtiExpress: spoVAC | |
Metabolic function and regulation of this protein in SubtiPathways: Lys, Thr | |
MW, pI | 15 kDa, 9.461 |
Gene length, protein length | 450 bp, 150 aa |
Immediate neighbours | spoVAD, spoVAB |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context ![]() This image was kindly provided by SubtiList
| |
Expression at a glance PubMed![]() |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU23420
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P40868
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
- Peter Setlow, University of Connecticut Health Center, USA
Your additional remarks
References
Yunfeng Li, Andrew Davis, George Korza, Pengfei Zhang, Yong-qing Li, Barbara Setlow, Peter Setlow, Bing Hao
Role of a SpoVA protein in dipicolinic acid uptake into developing spores of Bacillus subtilis.
J Bacteriol: 2012, 194(8);1875-84
[PubMed:22328679]
[WorldCat.org]
[DOI]
(I p)
Venkata Ramana Vepachedu, Peter Setlow
Role of SpoVA proteins in release of dipicolinic acid during germination of Bacillus subtilis spores triggered by dodecylamine or lysozyme.
J Bacteriol: 2007, 189(5);1565-72
[PubMed:17158659]
[WorldCat.org]
[DOI]
(P p)
Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190]
[WorldCat.org]
[DOI]
(P p)
Venkata Ramana Vepachedu, Peter Setlow
Analysis of the germination of spores of Bacillus subtilis with temperature sensitive spo mutations in the spoVA operon.
FEMS Microbiol Lett: 2004, 239(1);71-7
[PubMed:15451103]
[WorldCat.org]
[DOI]
(P p)
Federico Tovar-Rojo, Monica Chander, Barbara Setlow, Peter Setlow
The products of the spoVA operon are involved in dipicolinic acid uptake into developing spores of Bacillus subtilis.
J Bacteriol: 2002, 184(2);584-7
[PubMed:11751839]
[WorldCat.org]
[DOI]
(P p)
I Bagyan, J Hobot, S Cutting
A compartmentalized regulator of developmental gene expression in Bacillus subtilis.
J Bacteriol: 1996, 178(15);4500-7
[PubMed:8755877]
[WorldCat.org]
[DOI]
(P p)
V Azevedo, A Sorokin, S D Ehrlich, P Serror
The transcriptional organization of the Bacillus subtilis 168 chromosome region between the spoVAF and serA genetic loci.
Mol Microbiol: 1993, 10(2);397-405
[PubMed:7934830]
[WorldCat.org]
[DOI]
(P p)
B Moldover, P J Piggot, M D Yudkin
Identification of the promoter and the transcriptional start site of the spoVA operon of Bacillus subtilis and Bacillus licheniformis.
J Gen Microbiol: 1991, 137(3);527-31
[PubMed:1903432]
[WorldCat.org]
[DOI]
(P p)
J Errington, J Mandelstam
Use of a lacZ gene fusion to determine the dependence pattern and the spore compartment expression of sporulation operon spoVA in spo mutants of Bacillus subtilis.
J Gen Microbiol: 1986, 132(11);2977-85
[PubMed:3114420]
[WorldCat.org]
[DOI]
(P p)
P Fort, J Errington
Nucleotide sequence and complementation analysis of a polycistronic sporulation operon, spoVA, in Bacillus subtilis.
J Gen Microbiol: 1985, 131(5);1091-105
[PubMed:3926949]
[WorldCat.org]
[DOI]
(P p)
J Errington, J Mandelstam
Genetic and phenotypic characterization of a cluster of mutations in the spoVA locus of Bacillus subtilis.
J Gen Microbiol: 1984, 130(8);2115-21
[PubMed:6432957]
[WorldCat.org]
[DOI]
(P p)