spoIVCA

spoIVCA
168

site-specific DNA recombinase required for creating the [gene|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK] gene (excision of the [category|SW.5.1.3|Skin element])

locus
BSU_25770
Molecular weight
57.31 kDa
pI
9.5
Protein length
Gene length
function
excision of the [category|SW.5.1.3|Skin element], creation of the [gene|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK] gene
product
site-specific DNA recombinase
essential
no
synonyms
spoIVCA, cisA

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1961 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,653,371  2,654,873
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The protein
Protein family
N-terminal part: [wiki|site-specific recombinase resolvase family] (according to UniProt)
[wiki|Domains]
[wiki|Resolvase/invertase-type recombinase catalytic domain] (aa 1-144) (according to UniProt)
Structure
[AF|P17867]
Expression and Regulation
Operons
genes
[gene|318618D2FB485EA2A08AD8468B1144ACC1CA2B99|spoIVCA]
description
[Pubmed|2105293]
regulation
expressed early during sporulation in the mother cell ([protein|search|SigE], [wiki|SpoIIID]) [Pubmed|15699190,2105293,7966271]
regulatory mechanism
[protein|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID]: activation, [Pubmed|7966271], in [regulon|protein:90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID regulon]
sigma factors
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [Pubmed|15699190,2105293], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
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[gene|318618D2FB485EA2A08AD8468B1144ACC1CA2B99|spoIVCA]

2024-03-28 02:54:34

ghost

40

665efd42cac13c813dc37ca67ffe676db9f20143

31F546227EB0B641456A2CFD828504BB8CDA239F

Biological materials
Mutant
BKE25770 ([gene|318618D2FB485EA2A08AD8468B1144ACC1CA2B99|spoIVCA]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE25770 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CACCCTGAATCTCCTTCCTA,  downstream forward: _UP4_TTTCAATCAATCGGTGCAGA
BKK25770 ([gene|318618D2FB485EA2A08AD8468B1144ACC1CA2B99|spoIVCA]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK25770 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CACCCTGAATCTCCTTCCTA,  downstream forward: _UP4_TTTCAATCAATCGGTGCAGA
References
2163341,2105293,2841290,7966271

318618D2FB485EA2A08AD8468B1144ACC1CA2B99

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Time of last update: 2024-03-28 19:39:23

Author of last update: Jstuelk